Kojima has confirmed that his next game won't involve Del Toro or Reedus or anyone else.
He does hope to do something with them someday in the future though, but it may be a very long while.
That's unfortunate. I obviously haven't been following the Kojima-Reedus-Del Toro relationship as close as I probably should, but I do hope that the three of them do work together in the future. Also, that gif is wonderful. I wouldn't mind a very fantasy-esque horror game that's reminiscent of Pan's Labyrinth