I had no idea what to do with the damn Aglaophotis the first time. I correctly believed it was going to feature in a boss fight, but incorrectly tried to use it on the final boss (I can't remember which version it was) and was killed dead.
Second time around, I knew better and Good + was mine.
If I didn't have, you know, an arsenal of weaponry, I MAY have out of desperation chucked the bottle at her, simply because I figure if I had no weapons I would be dodging her to avoid being killed (since I couldn't kill her before she ran out of ammo), which would obviously lead to the situation where the Aglaophotis is used, and since I wouldn't chuck healing items at her I would choose the bottle, since a bottle to the face can be effective against people who are hostile towards you.
I voted for Good +, because I like both Harry and Cybil. I like that there is a best ending in Silent Hill, as opposed to the 'best of' endings some of the other games in the series have. I do support Good - as the canon ending, because Cybil didn't really need to live and she could have needlessly complicated SH3.
That said (Silent Hill 3 spoilers ahead, just to be safe):
I think they could have done something simple to back up G+, like having had a postcard on the fridge you could examine and it would say something like 'Postcard from England from my aunt Cybil. An old friend of my Dad's.'