I'll be honest: I don't really like
The Room.
Far as I'm concerned, it's just a dime-a-dozen Japanese ghost story (
He was stuck to the bottom of the lid!!) that tosses all of the gameplay advancement that had culminated in SH3 out the window. I don't understand why they went that (control/gameplay) route, and it's the biggest reason why the apocryphal theory that
The Room was originally an independent game gained so much traction in the Western community.
Amusingly (and irksomely), nostalgia has increased since game development moved over the ocean. Since
The Room was Japanese, it therefore got promoted to the "good ol' days." It was, to say the least, controversial back in 2004 and '05. That's the way I see it, of course, and there are always exceptions (like people who always did like it, for one reason or another).
Naturally, my first reaction is: "If you feel like you're wasting your time, you probably are."
That said, you do seem somewhat invested in the outcome of
The Room, so lemme see if I can offer any advice...
Back when I was playing (I haven't really replayed it since, oh, '06 at the latest), I remember finding a "safe" room and leaving Eileen in there as I ran around and cleared out the monsters. These rooms typically were small and only had items in them (you can leave her somewhere where you cleared out the monsters, but there's always a chance they might respawn and damage her while you're away).
Eileen accumulates damage based, unless I'm mistaken, on the "danger level" of a room and how much time you leave her in there. So leave her someplace safe and work fast so she accumulates as little as possible. Manage your save files in such a way that, if the results aren't to your liking (she ends up looking like a rotten apple), you can reload and try again.
Also, a very important note, and I'll put it in spoiler tags even though it has nothing to do with the story:
Eileen can't die. She'll look terrible, but she cannot die until you trigger a certain story event. How much damage she takes is significant, but she won't just keel over in the middle of the forest.
That should relieve some of the stress you're under.
Also, there are four "special" ghosts and four Swords of Obedience. Use that to your advantage. Follow this, and your only worry will be Mr. Cobain, himself.
Careful, though: He'll still try to eat your cancer.